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For some people, weight loss can become more difficult as they reach middle age and grow older. Losing weight after hitting the 50 year mark can be especially challenging due to a host of changes that happen within the body around that age.
Hormonal and metabolism changes can affect both men and women, albeit in different ways. If you’re someone who is struggling to maintain a healthy weight, the good news is that there are lots of ways to support weight management and help you reach your weight loss goals.
In this article, we’ll cover exactly why weight loss after 50 is so hard and share a few tips to help you combat age-related weight gain.
Losing Weight as You Age

Why exactly does losing weight seem to become more and more difficult as you age? The answer to this question is very complex, as there are a variety of factors that may be stunting your weight loss as you get older.
Hormonal changes and changes in activity levels are just a few factors that may make weight management more difficult for aging adults. Some research shows that lipid turnover in the fat tissue can slow down with age, making it harder to keep off extra weight.
Another important factor may be declining muscle mass. Age related muscle loss, or sarcopenia, can lead to a slowing down of metabolic rate. This is because muscle is more metabolically active than fat, and loss of this metabolically active tissue can affect calories burnt.
5 Factors That Can Make Weight Loss Harder with Age
Now that you have a better idea of some of the factors that can contribute to difficulty in losing weight, let’s take a deeper look at what the research says about each of these changes.
1) Hormonal Changes

Researchers have found that hormonal changes around midlife can lead to increased weight gain. Due to disturbances of hormones that can come with aging, the prevalence of subclinical hypothyroidism can increase, making more older adults likely to gain weight as they age.
At the same time, research shows that insulin secretion decreases with age, which may increase the likelihood for insulin resistance and elevated glucose levels that may be stored as fat.
Studies show that leptin levels can also decrease with age, but significantly more so in women than men. This decrease may also affect age-related weight gain for some people.
2) Menopause in Women
When it comes to women’s health, another age-related hormonal shift that can lead to weight gain is menopause. Menopause is marked by changes in sex hormones. These changes include decreased estrogen levels and increased androgens. This can affect fat distribution and weight gain.
One review investigating menopause found that menopause specifically contributes to abdominal obesity. This menopause-related increase in abdominal fat may be stubborn and hard to lose for many.
While men may not experience menopause, they do experience their own unique hormonal changes through aging that can lead to weight gain. Research has shown that age-related weight gain in men is associated with a decrease in total testosterone, free testosterone, and sex hormone binding globulin, or SHBG.
3) Changes in Muscle Mass

As you age, you may start to lose muscle mass, though this tends to affect men more than women. Muscle quality can also decrease with age, which can lead to a loss of strength. Interestingly, a loss of muscle mass is associated with some of the age-related hormonal imbalances we mentioned earlier.
Other hormonal factors include changes in androgens such as testosterone. Because testosterone plays an important role in muscle strength and mass in men, lower levels of this androgen in the aging population contributes to decreased muscle mass.
Growth hormones such as IGF-1 contribute to muscle mass and also decline through aging. Thus, the decrease in this hormone can lead to reduced muscle mass. A reduction in muscle mass can reduce metabolic rate, making weight gain much easier for older adults.
There is limited evidence to suggest that changes in estrogen levels during menopause contributes to sarcopenia in women, however. This may be why sarcopenia affects men more than it affects women.
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4) Poor Diet
A poor diet in older adults is often attributed to factors such as a gradual loss of taste and smell, which can lead to adding more salt or choosing more processed foods with hyperconcentrated flavors. Not only are these foods often higher in calories, but they can lead to inflammation and poor blood glucose levels for some people.
Both inflammation and poor glucose levels can aggravate the hormonal changes with insulin, and IGF-1, and lead to weight gain. Processed foods may also be low in nutrients such as protein that can support muscle growth, and have other potential effects on your well being.
5) Sedentary Lifestyle

A sedentary lifestyle is another factor that can lead to weight gain as you age, especially when paired with other factors such as a poor diet. This type of lifestyle is common in older adults, and studies have found a link between sedentary lifestyles and increased risk of obesity and mortality.
In older adults, factors such as having a smaller social circle, restricted access to spaces you can walk around in, or feeling too embarrassed to go to the gym may contribute to sedentary behavior. However, not moving your body or getting appropriate exercise can contribute to a loss in muscle mass and reduce your metabolic rate.
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Heather is a Registered and Licensed Dietitian Nutritionist (RDN, LDN), subject matter expert, and technical writer, with a master's degree in nutrition science from Bastyr University. She has a specialty in neuroendocrinology and has been working in the field of nutrition—including nutrition research, education, medical writing, and clinical integrative and functional nutrition—for over 15 years.